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Stu Williamson received Fullbright-Cancer Research UK Scholar Award
18 May 2018
Huge congratulations to Stuart Williamson, from our Clinical and Experimental Pharmacology group, who received a Fulbright-Cancer Research UK Scholar Award to enable him to research at Stanford University on one of the most well-regarded and impactful scholarship programmes in the world.
 
Results released from lung cancer FLAURA trial involving Centre researcher
22 January 2018
Results from the Phase III FLAURA trial which provide data for osimertinib use in the 1st-line treatment of adult patients with locally advanced or metastatic epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) have been published in the New England Journal of Medicine.
 
Prof Caroline Dive awarded CBE in the New Year's Honours list
01 January 2018
Prof Caroline Dive awarded CBE in the New Year's Honours list
 
Lung cancer treatment could be having negative health effect on hearts
25 September 2017
Radiotherapy treatment for lung cancer could have a negative effect on the health of your heart new research has found.
 
Advanced radiotherapy improves lung cancer survival rates
04 July 2017
A ten-year University of Manchester and Christie NHS Foundation Trust study which used advanced radiotherapy techniques in patients with limited-stage small cell lung cancer (SCLC) has achieved the best survival rates and lowest toxicity ever reported.
 
Cancer Research UK appoints Professor Charles Swanton as its chief clinician
21 June 2017
Cancer Research UK is pleased to announce the appointment of Professor Charles Swanton as its new chief clinician. Prof Swanton, who will also join the charity’s executive board later this summer, has enjoyed a long association with Cancer Research UK. He now leads a team at the Francis Crick Institute in London, working on an internationally acclaimed clinical study, TRACERx, analysing how lung cancer develops.
 
Lung Cancer Centre of Excellence Co-Lead Charles Swanton elected EMBO member
20 June 2017
Last Friday, the European Molecular Biology Organisation (EMBO) announced that Charles Swanton, Group Leader at the Francis Crick Institute, has been elected to its membership for his contribution to the life sciences.
 
Tracking unstable chromosomes helps predict lung cancer’s return
27 April 2017
Scientists at UCL, UCLH and the Francis Crick Institute have found that unstable chromosomes within lung tumours increase the risk of cancer returning after surgery, and have used this new knowledge to detect relapse long before standard testing.
 
Experimental blood test could offer a glimpse of the future for doctors treating lung cancer
26 April 2017
Being able to predict accurately whether a patient’s cancer would come back after treatment would help doctors stay one step ahead of the disease.
 
Manchester to host the second Cancer Research UK Lung Cancer Centre of Excellence Conference
11 April 2017
The CRUK Lung Cancer Centre of Excellence is thrilled to announce that we will be holding our second Conference at the Midland Hotel in Manchester, from 3rd-5th December 2017. Our Conference will bring together experts across a range of disciplines to discuss the latest advances in lung cancer research and how we can continue to drive forward progress.
 
Lung cancer early diagnosis rates soar during UK-first CT Community Scanner Pilot in Manchester by UHSM
16 March 2017
Lung cancer early diagnosis rates have soared during a targeted screening pilot in Manchester where on-the-spot CT scans were offered in shopping area car parks.
 
Nose swab detects tobacco damage linked to lung cancer in smokers
01 March 2017
A sample of cells taken from the inside of the nose could be used to indicate the damage caused to cells in the lung by smoking, a new US study has found.
 
Hitgen and Cancer Research UK's Manchester Institute enter licence agreement in lung cancer
28 February 2017
Cancer Research UK, Cancer Research Technology (CRT), the charity’s commercial arm, and HitGen Ltd, a privately held biotech company focused on early drug discovery, announced today that they have entered into a licence agreement to develop a novel class of drugs against lung cancer.
 
Yorkshire Cancer Research funds cross-pennine partnership
06 February 2017
Researchers at The Christie NHS Foundation Trust will join forces with Leeds Teaching Hospitals NHS Trust to improve radiotherapy treatment for patients with lung cancer.
 
The CRT Pioneer Fund and Cancer Research UK's Manchester Institute nominate cancer drug candidate
20 January 2017
The Cancer Research Technology Pioneer Fund LP (CPF) today (Friday) has announced it will further develop a promising class of cancer drugs called RET inhibitors, through a collaboration with the Cancer Research UK Manchester Institute Drug Discovery Unit, at The University of Manchester.
 
Landmark study provides insight into chemotherapy treatment for lung cancer patients
16 January 2017
A research team, led by UCL and consisting of members of the CRUK Lung Cancer Centre of Excellence at Manchester and UCL, has published the results of a highly anticipated clinical trial comparing platinum and non-platinum chemotherapy in the Journal of Clinical Oncology. The aim of this trial was to see whether doctors could select the most effective chemotherapy treatment for advanced lung cancer patients.
 
Study suggests small cell lung cancer should not be treated as single disease
13 January 2017
A new study in mice suggests that a type of lung cancer could be split into two different diseases based on cells’ molecular fingerprints.
 
Lung Cancer Centre Student and Postdoc York Winter Workshop a huge success
08 December 2016
The CRUK Lung Cancer Centre of Excellence held its second student and postdoc meeting on Thursday 1st and Friday 2nd December 2016 at the Principal York Hotel, York. Our hugely successful Winter Workshop brought together 89 junior researchers, including students, postdocs and clinical research fellows, and theme leads working in the lung cancer field.
 
Blood test could predict best treatment for lung cancer
22 November 2016
A blood test could predict how well small-cell lung cancer (SCLC) patients will respond to treatment, according to new research published in Nature Medicine by Centre Co-Lead Caroline Dive and her team.
 
Charles Swanton, Co-Lead of the CRUK Lung Cancer Centre of Excellence, is the 2016 recipient of the Biochemical Society's GlaxoSmithKline Award
21 November 2016
The award is given in recognition of research leading to new advances in medical science and is specifically intended to recognize mid-career biochemists who completed their PhD less than 20 years ago.
 
Circulating tumour cells in small cell lung cancer reveal vasculogenic mimicry as a mechanism of dissemination and chemoresistance in this recalcitrant tumour
11 November 2016
The Clinical and Experimental Pharmacology group, from the Cancer Research UK Manchester Institute, has worked with scientists in the US to explore vasculogenic mimicry – where tumour cells form themselves into blood vessels – in small cell lung cancer (SCLC)
 
Achilles Therapeutics launched with funds of £13.2 million to develop immunotherapies for cancer, involving Lung Cancer Centre UCL theme leads
05 October 2016
Sycona LLP and Cancer Research Technology (CRT) announce the formation of Achilles Therapeutics Ltd today. The new private company will bring together world-class research from UCL (University College London) and the Francis Crick Institute, funded by Cancer Research UK and the National Institute for Health Research (NIHR).
 
Fiona Blackhall among three Christie consultants made professors
27 September 2016
Three consultants from The Christie NHS Foundation Trust, one of Europe's leading cancer centres, have been made professors, including Fiona Blackhall, Lung Cancer Centre Theme Lead for Clinical Trials at Manchester.
 
E-cigarettes may have helped 18,000 people quit smoking in 2015
14 September 2016
E-cigarettes may have helped about 18,000 people in England to give up smoking in 2015, according to new research published in the British Medical Journal today.
 
CRUK Lung Cancer Centre of Excellence co-lead Professor Charles Swanton among six leading scientists awarded Royal Society Research Professorships for his work in lung cancer
06 September 2016
Professor Swanton is one of six world class scientists who have been awarded Royal Society Research Professorships. These prestigious posts usually run for up to ten years and provide long-term support for internationally recognised scientists of exceptional accomplishments from a range of diverse areas including biochemistry, genetics, chemistry, developmental biology and physics.
 
Lung cancer patients whose tumour has spread to the brain could be spared radiotherapy
04 September 2016
Patients with non-small cell lung cancer which has spread to the brain could be spared whole brain radiotherapy as it makes little or no difference to how long they survive and their quality of life, according to a Cancer Research UK-funded clinical trial published today in The Lancet.
 
Professor Henning Walczak added to the CRUK Lung Cancer Centre of Excellence Winter Workshop programme
25 August 2016
We are excited to announce that our Centre co-Theme Lead for Basic Science Professor Henning Walczak will be speaking in the 'Mechanisms Driving Lung Tumorigenesis' session on Thursday 1st December, at our student and postdoc Winter Workshop 2016.
 
Registration opens for CRUK Lung Cancer Centre of Excellence Winter Workshop 2016!
12 August 2016
We are pleased to announce that registration is now open for our Winter Workshop, which will be taking place on Thursday 1st-2nd December 2016 at the Royal York Hotel, York.
 
CRUK Lung Cancer Centre of Excellence scientists to speak at free event in London next month
09 August 2016
The Future Horizons in Lung Cancer meeting will be held at the Royal Society of Medicine in London, 1st-2nd September 2016, and will feature a dynamic host leading researchers discussing topics such as radiotherapy, immunotherapy and tumour heterogeneity.
 
Dr Nicholas McGranahan, CRUK Lung Cancer Centre of Excellence scientist based at UCL/the Francis Crick Institute, awarded Pontecorvo prize
29 July 2016
This year’s Pontecorvo prize for Best PhD Thesis has been awarded to Dr Nicholas McGranahan, an outstanding young scientist at University College London and the Francis Crick Institute.
 
AACR Scholar-in-Training Award for Lung Cancer Centre of Excellence Postdoctoral Research Fellow
13 July 2016
Congratulations to Dr Pedro Torres-Ayuso, from the Signalling Networks in Cancer group at the CRUK Manchester Institute and Lung Cancer Centre of Excellence, who won an American Association for Cancer Research (AACR) Scholar-in-Training Award, sponsored by Abbvie.
 
Caroline Dive wins AstraZeneca Prize for Women in Pharmacology
04 July 2016
We are proud to announce that our Centre co-lead Professor Caroline Dive has recently been awarded a prestigious British Pharmaceutical Society prize.
 
University of Manchester and Lung Cancer Centre of Excellence researchers join forces with US 'cancer moonshot' to develop advanced cancer cell detection technology
29 June 2016
Cancer Research UK researchers based at The University of Manchester and the US government’s National Cancer Institute have announced that two teams will work together to radically accelerate progress against cancer, in one of the first international collaborations inspired by US Vice-President Joe Biden’s Cancer Moonshot.
 
Marie Curie Fellowship for Centre of Excellence Postdoctoral Research Fellow
22 June 2016
Congratulations to Dr Pedro Torres-Ayuso on his success in obtaining a prestigious Marie Sklodowska-Curie Individual Fellowship. The MSCA, funded through the European Commission, supports the best or most promising researchers to enhance career development and training towards establishing an independent position.
 
Centre of Excellence theme lead Corinne Faivre-Finn wins International Researcher of the Year at The Christie Staff Awards
16 June 2016
Professor Faivre–Finn was awarded International Researcher for her work leading a ground-breaking study into radiotherapy for people with small cell lung cancer.
 
Twice a day radiotherapy halves treatment time and is equally good at treating small cell lung cancer
06 June 2016
A University of Manchester-led trial has found that having radiotherapy once a day for six and a half weeks or twice a day for three weeks – when combined with chemotherapy – is equally good at treating small cell lung cancer that hasn’t spread.
 
Researchers find a genetic new target for most common lung cancer
14 May 2016
Research in Manchester has identified mutations in lung cancer that are key to tumour growth, offering a new way to differentiate and treat some patients with the disease.
 
Tumours contain the seeds of their own destruction
03 April 2016
Scientists have made a groundbreaking discovery in understanding how the genetic complexity of tumours can be recognised and exploited by the immune system, even when the disease is at its most advanced stages.
 
Centre's inaugural conference a resounding success
01 March 2016
Cancer Research UK's Lung Cancer Centre of Excellence hosted a hugely successful three-day inaugural conference at the Manchester Midland Hotel, from December 13th-15th 2015
 
Exploring routes for lung cancer spread
03 December 2015
Researchers in Manchester have compared different ways to model lung cancer that has spread to other parts of the body, offering a better understanding of how to test potential treatments for advanced disease.
 
Manchester collaboration for early detection of lung cancer
05 August 2015
The University of Manchester has signed a collaboration agreement with Abcodia to perform proteomics studies on a cohort of non-small cell lung cancer cases from the UKCTOCS biobank, with the aim of discovering new blood-based biomarkers for earlier detection of the disease.
 
Manchester lung cancer research features at Royal Society
30 July 2015
Cutting-edge research from Manchester that could improve treatment for lung cancer patients was recently showcased at the Royal Society’s Summer Science Exhibition in London.
 
Overcoming why a new treatment is resisted by lung cancer
29 July 2015
A promising agent for the treatment of cancer has so far had little effect on the most common lung tumours, but new research from The University of Manchester has suggested how this resistance might be overcome.
 
Centre holds first ever Summer Conference
22 July 2015
The Centre successfully held its first 'Student and Post Doc Summer Conference' recently in York.
 
Centre scientists recognised for excellence in research
11 May 2015
Professor Charles Swanton and Professor Caroline Dive are two of 48 researchers from across the UK to have been recognised for their contribution to the advancement of medical science by election to the Fellowship of the Academy of Medical Sciences.
 
Profiling approach to enable right lung cancer treatment match
05 May 2015
Manchester researchers have tested a new way to genetically profile lung cancer samples, potentially allowing doctors to more easily identify the most appropriate treatment for patients.
 
Scientists decipher key steps in cancer development to improve treatment
15 April 2015
Scientists have discovered the timing of key genetic mistakes that fuel tumour growth.
 
Body’s cancer defences hijacked to make lung cancers more aggressive
02 April 2015
Scientists at UCL have discovered that a vital self-destruct switch in cells is hijacked - making some non small cell lung cancers more aggressive.
 
Combination cell-gene therapy for lung cancer to be tested in UK patients
06 March 2015
A pioneering new combined cell-gene therapy to treat lung cancer will be tested in NHS patients this year.
 
New technique cuts treatment waiting time for lung cancer patients
05 February 2015
UCL research has revealed that a new technique for investigating lung cancer spread will halve the time between first hospital visit and treatment.
 
Potential new tool to monitor radiotherapy side effects
07 January 2015
Researchers in Manchester have investigated a patient-centred approach to assessing the side effects of radiotherapy and have shown that it may be able to improve the detection and management of treatment-related toxicity.
 
Scientists zero in on how lung cancer spreads
24 December 2014
Cancer Research UK scientists have taken microscopic images revealing that the protein ties tethering cells together are severed in lung cancer cells – meaning they can break loose and spread.
 
More evidence for impact of lung cancer targeted therapy from trial
04 December 2014
An international study involving Manchester researchers has found that for previously untreated lung cancer patients with a particular genetic change, a new targeted therapy is better than standard chemotherapy.
 
Risk stratification model may aid lung cancer staging and treatment decisions
03 December 2014
Manchester researchers have explored a risk stratification model based on lymph node characteristics and have shown a high level of confidence in confirming a true lack of lung cancer in the lymph nodes of patients with a negative lymph node sample.
 
£50M CRT Pioneer Fund announces investment to develop lung cancer drugs at Cancer Research UK Manchester Institute
21 November 2014
The Cancer Research Technology Pioneer Fund (CPF) have announced a collaboration with the Cancer Research UK Manchester Institute Drug Discovery Unit to develop a promising class of drugs called RET inhibitors to treat cancer.
 
Scientists trigger self-destruct switch in lung cancer cells
31 October 2014
Cancer Research UK scientists have found a drug combination that can trigger the self-destruct process in lung cancer cells - paving the way for new treatments.
 
No survival benefit from combination therapy for lung cancer patients with multiple brain metastases
27 October 2014
A study led by researchers from UCL, working alongside doctors from Manchester and other UK hospitals, has found no benefit for a combined treatment approach in lung cancer patients with secondary brain tumours.
 
Researchers reveal lung cancer can stay hidden for over 20 years
10 October 2014
Cancer Research UK scientists have discovered that lung cancers can lie dormant for over 20 years before suddenly turning into an aggressive form of the disease, according to a study published in Science today.
 
Manchester study investigates methods for lung cancer sampling
09 October 2014
Researchers in Manchester have investigated which patients with lung cancer could most benefit from undergoing an alternative method for tissue biopsy – potentially reducing the risk of a collapsed lung for some patients.
 
New method to increase chance of survival for some lung cancer patients
16 September 2014
Scientists from The University of Manchester have found that offering radiotherapy to patients with small cell lung cancer in addition to chemotherapy improves their chances of survival two years after treatment.
 
Study shows potential method to better control lung cancer using radiotherapy
29 August 2014
Manchester scientists are working out how to safely increase the radiotherapy dose given to lung cancer patients – potentially offering improved local control and survival.
 
Lung cancer diagnosis tool shown to be safe and effective for older patients
05 August 2014
A recent study in Manchester has found that a procedure to take tissue samples from lung cancer patients can be used safely in the elderly – allowing doctors to make a more accurate diagnosis and to choose appropriate treatment.
 
New drug active against most aggressive type of lung cancer cells
11 July 2014
Manchester scientists have shown that a new drug could prove useful in treating small cell lung cancer - the most aggressive form of lung cancer.
 
Cancer Research UK launches visionary new Lung Cancer Centre of Excellence
01 July 2014
Cancer Research UK is bringing together leading researchers from London and Manchester in a groundbreaking new Lung Cancer Centre of Excellence.
 
‘Liquid biopsy’ offers new way to track lung cancer
02 June 2014
Scientists have shown how a lung cancer patient’s blood sample could be used to monitor and predict their response to treatment – paving the way for personalised medicine for the disease.
 
Lung cancer rates climb in women in the North West while falling in men
20 March 2014
In the North West, lung cancer rates in women have risen by nearly a quarter (23 per cent) over the last twenty years according to new Cancer Research UK figures.
 
Scientists in Manchester discover new protein involved in lung cancer
28 February 2014
Scientists from The University of Manchester – part of the Manchester Cancer Research Centre – have discovered a new protein that is involved in cancer and inflammation in lung tissue.
 
Fighting the invasion: what makes lung cancer cells spread?
17 February 2014
Scientists in Manchester are a step closer to understanding how lung cancer cells are able to spread into surrounding tissue and now believe that specialised channels that let sodium ions move into the cell play a crucial role.
 
New research to revolutionise understanding of lung cancer evolution
18 July 2013
In a world first, a new Cancer Research UK study involving Manchester and UCL scientists will unlock lung cancer’s secrets, tracking in real time how lung tumours develop and evolve as patients receive treatment.
 
Genetic screen finds new treatment targets for lung cancer
08 July 2013
Cancer Research UK scientists are the first to use an efficient new screening strategy to identify gene faults in tumour cells that are possible drug targets for the most common form of lung cancer, according to new research published in PNAS.
 

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